In Nancy Drew: Stay Tuned for Danger, the player will control private detective Nancy Drew. A woman comes to New York and stays with an actress named Mattie. Her friend regularly receives threats. He receives parcels with spoiled desserts and letters with negative content. The actress asks to investigate this case. Before the campaign, it is possible to choose the difficulty: easy, normal and difficult. You can control the detective from the first person. At the bottom of the screen there are 2 panels: 4 inventory slots and the characters' lines. Who will Nancy Drew meet besides the actress Mattie:
- Ralph - works as a security guard at the production center where the series is being filmed, strict character;
- Lilian Weiss - director, shoots the TV series Fire of Love, 1 of the suspects;
- Millie Strafford - head of the company that is engaged in filming TV series and promoting stars, the chief assistant director for props;
- Dylan Powers - manager of Mattie and other actors, is in a quarrel with Rick;
- Rick Arlen - media personality, a guy who receives threats from unknown people.
In Nancy Drew Stay Tuned for Danger, the user will talk to non-player characters, move from 1 location to others, carefully search rooms in search of evidence. After meeting Mattie, Nancy will go to the building where the Fire of Love is being filmed. The director of the film will kick the girl out. To return to the center, the detective will have to get a job in the company.